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On Saturday night, the Chula Vista Fire Department and police were called to a major crash on the 400 block of L Street.
When they arrived, they found an RV on the wrong side of the road, partially lodged in a semi-trailer.
The RV was so severely damaged that first responders had to lift the wreckage in order to rescue the driver, who was trapped under the dash and the trailer.
A couple with their dog, believed to be homeless, were in a parked SUV that was also struck.
However, they escaped serious injury.
The driver of the RV was transported to the hospital with major traumatic injuries.
The two dogs in the RV were rescued and taken by Chula Vista Animal Control for further care.
It is not yet known if drugs or alcohol were involved in the crash. An investigation is ongoing.